Director Division of Bioinformatics and Biostatistics
Dr. Tong is Director of Division of Bioinformatics and Biostatistics at NCTR/FDA. He is also Senior Biomedical Research Service which only some 70 scientists/reviewers at FDA hold that title. He has served science advisory board for several multi-institutional projects in Europe and USA. He also holds adjunct appointment at several universities. He is the founder and board chairperson of international MAQC Society. His primary research interest is to apply bioinformatics, chemoinformatics, molecular modeling and data analytics for biomarker discovery, drug safety, drug repurposing, pharmacogenomics/toxicogenomics, and precision medicine. Currently, he directs several FDA mission-critical projects in his division: (1) Supervising and leading the FDA-led community wide MicroArray Quality Control (MAQC) consortium to analyze technical performance and practical utility of emerging genomics technologies with emphasis on regulatory application and personalized medicine; (2) Development of Liver Toxicity Knowledge Base (LTKB) to address the drug safety concerns related to drug-induced liver injury (DILI); (3) Designing and developing computer based technology to support the FDA’s effort on bioinformatics and scientific computing (e.g., development of the FDA genomic tool, ArrayTrack, to support the pharmacogenomics data review in FDA); (4) developing machine learning and AI for digital health and drug repositioning; and (5) conducting molecular modeling and QSARs on various toxicological endpoints with specific interest in estrogen, androgen, and endocrine disruptor. Dr. Tong has published around 300 peer-reviewed papers and book chapters.
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